DNA is often described as the instruction manual for building the fundamental components of life. Proteins are helpers that ...

One of the biggest hurdles in developing an HIV vaccine is coaxing the body to produce the right kind of immune cells and ...

Life runs on instructions you never see. Every cell reads DNA, turns that message into RNA, and then builds proteins that ...

Unrepaired DNA-protein crosslinks (DPCs) – highly toxic tangles of protein and DNA – cause a process that leads to premature ...

Although DNA is tightly packed and protected within the cell nucleus, it is constantly threatened by damage from normal ...

Researchers have uncovered a microscopic weapon that can literally tear viruses apart from the inside, a single protein that ...

Researchers have shown that harmful bonds between protein and DNA fuel immune attack in progeria. Pumping up a protein that cuts these bonds could prevent symptoms.

A new mouse study found that unrepaired DNA-protein crosslinks activate inflammatory signaling pathways that trigger early aging disorders.

Gene therapy holds the promise of preventing and curing disease by manipulating gene expression within a patient's cells. However, to be effective, the new gene must make it into a cell's nucleus. The ...

Overcoming tumor resistance to chemotherapy drugs has long been a challenge for oncology clinicians and researchers. Now, a new study suggests that blocking a key protein, p300, may force damaged ...