This integrated approach, combining histological analysis and single-nucleus RNA sequencing, revealed that the senescence and depletion of nucleus pulposus progenitor cells (NPPCs) represent ...

HOUSTON--(BUSINESS WIRE)--MRI analysis of patients who received intradiscal injections of human dermal fibroblasts (HDFs) shows significant improvement in disc height after six months. This is the ...

If the tough outer cover of a disc that acts as a cushion between 2 bones in the lower part of spine (the lumbar vertebrae) tears, the soft centre can bulge through the tear. This is called herniation ...

The spinal column consists of 24 vertebrae that provide axial support to the torso and protection to the spinal cord that runs through its central cavity. The vertebrae are connected by means of ...

Researchers at Uppsala University have developed a gel inspired by cow slime for patients suffering from disk herniation. By adding the mucin gel immediately after surgery, it is possible to create a ...

Schematic diagram depicting the mechanism of the rigid matrix regulating cell glycolysis in degenerated NPCs. In degenerated NP tissue, MRTF-A was activated by increased matrix stiffness and ...

Researchers have developed a gel inspired by cow slime for patients suffering from disc herniation. By adding the mucin gel immediately after surgery, it is possible to create a protective barrier ...

Our spine is a mechanical structure that supports our body when standing and sitting and allows us to bend, stoop, squat, twist and turn. With the exception of the first two vertebrae in our neck, ...

This procedure is done under local anaesthesia, with the patient sedated and lying face down. It aims to relieve low back pain by delivering heat energy to the damaged disc. A needle is inserted into ...