In most eukaryotes, the inheritance of mitochondrion and its DNA (mtDNA) is strictly maternal, despite the fact that a spermatozoon can inject up to 100 functional mitochondria into the oocyte during ...

The 100 or so organelles in sperm are swamped by hundreds of thousands of mitochondria embedded in each egg cell — each carrying the 37 genes in mitochondrial DNA. The contribution of only maternal ...

Doubly uniparental inheritance (DUI) of mitochondrial DNA (mtDNA) represents a rare and intriguing deviation from the standard model of strictly maternal inheritance. In bivalves, DUI manifests as the ...

An evolutionary trait of humans and most animals is that they inherit mitochondrial DNA exclusively from the mother, even though the father's spermatozoa have mitochondria. If spermatozoa have ...

Several human diseases arise due to defects in mitochondrial DNA (mtDNA), which is distinct from nuclear DNA and is inherited only from maternal ancestors. The prevention of these diseases by ...

University of Nevada, Reno researchers Jeanne and David Zeh of the Department of Biology have received a five-year, $650,000 grant from the National Science Foundation to investigate the effects of ...

Recombination occurs in human mitochondrial DNA, says a team from the Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, in a “proof of concept” paper in Science this week that ...

Mitochondrial donation through pronuclear transfer resulted in several live births and reduced transmission of pathogenic mitochondrial DNA (mtDNA) variants, researchers reported. The study involved ...

In September 6 Nature, Sofia Berlin and Hans Ellegren from Uppsala University, Sweden, examine the controversial clonal inheritance theory for vertebrate mitochondrial DNA (mtDNA) by following ...