Somatic mosaicism is the accumulation of mutations in DNA sequence or copy number in cellular genomes after fertilization. It is a known cause of neurological disorders including developmental brain ...

Somatic mosaicism has been observed previously in the lymphocyte population of patients with Fanconi anemia (FA). To identify the cellular origin of the genotypic reversion, we examined each ...

In most people, every cell in their body contains the same genetic information. However, sometimes people can have two or more genetically different sets of cells. This usually happens during fetal ...

Scientists at the University of Pennsylvania Perelman School of Medicine and the Children’s Hospital of Philadelphia (CHOP), have been able to examine a rare disease in which the maternal and paternal ...

Somatic chromosomal mosaicism is defined as the presence of two or more chromosomally distinct cell lines and represents a challenging task not only to detect but also to interpret. Owing to various ...

NA denotes not applicable, and ND not detected. Febrile seizures plus are febrile seizures that occur after the age when these seizures usually occur (3 months to 6 years) or when there are concurrent ...

Researchers identified mosaicism as a possible factor influencing Alzheimer’s risk in adults with Down syndrome, offering new insights into amyloid biomarkers and their broader implications for the ...

Please provide your email address to receive an email when new articles are posted on . Only 14.8% of patients with pigmentary mosaicism exhibited neurological abnormalities. Of 10 patients with a ...

In most people, every cell in their body contains the same genetic information. However, sometimes people can have two or more genetically different sets of cells. This usually happens during fetal ...

Our DNA makes us who we are, yet our genetic code is not the same from cell to cell. Errors during replication and cell division can cause sequences to shift or pieces to expand or get lost. Several ...