Endotoxins are lipopolysaccharides included in the cell wall of gram-negative bacteria. Endotoxins are co-purified during standard plasmid preparations resulting in lower survival rate of transfected ...
Rapid advances in the fields of DNA vaccines and gene therapy 1,2 have produced increased demands for large quantities of recombinant plasmid DNA. The problem is further exacerbated, as efficiency of ...
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