Grand Pharmaceutical Group Limited announced that its experimental drug STC3141 met the primary clinical endpoint in a Phase II trial conducted across sites in China, delivering a statistically ...

Researchers are exploring a new generation of biochemical markers that may help clinicians detect myocardial contusion. A frequently overlooked form of heart injury caused by blunt chest trauma, ...

Before a newly synthesized protein can undergo folding, it must be processed and transported to the correct location within the cell after emerging from the ribosome. N-terminal acetylation ...

State Key Laboratory of Discovery and Utilization of Functional Components in Traditional Chinese Medicine, Engineering Research Center for the Development and Application of Ethnic Medicine and TCM ...

Nucleosomes--which are composed of histone proteins (purple) wrapped in strands of DNA (green)--appear to regulate gene activity via inherent biophysical properties. For decades, scientists have known ...

The upper right portion illustrates viral nucleosome-like particles formed by co-occurring viral histone triplets and singlets. On the lower right, a network depicts distinct types of viral ...

Overproduction of histones also predicted aggressiveness of invasive breast cancer based on an analysis of 13 paraffin-embedded samples. One of the study’s co-first authors, Ye Zheng, PhD, then a ...

Key to identifying the readers of bivalency was the team's ability to create specifically modified histones and nucleosomes (where DNA is wound around histone proteins in a "beads on a string" ...

In our cells, 6 feet (1.8 m) of DNA gets crammed into chromosomes that fit inside a 6-µm-wide nucleus. The proteins that help pack up that genetic material are histones, which act as spools around ...

The latest chemistry news, including important research advances, business and policy trends, chemical safety practices, career guidance, and more. The work was led by Ian Maze, a neuroepigeneticist ...